Polyethylene glycol synthesis

Polyethylene oxide, or high-molecular-weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds.

Abbreviations: PEG

What is polyethylene glycol made from?

Polyethylene glycol (PEG) is made from ethylene glycol (ethane-1,2-diol), the main ingredient in antifreeze. When ethylene glycol (molecular weight, 62.07) polymerizes, reacts with itself (in water), the reaction yields a variety of products containing varying numbers of ethylene glycol units.

How is glycol synthesized?

Ethylene glycol was synthesized by catalytic hydrogenation of methyl glycolate, which was generated from the carbonylation and esterification of formaldehyde, an intermediate product prepared from syngas.

Is polyethylene glycol man made?

Polyethylene glycol (PEG) is a synthetic material with a wide range of clinical applications, as its functions can be modified by regulating the physical and chemical properties of it or its graft-related materials (Luo, 2004; Cui et al., 2015; Yang et al., 2015).

What is the difference between propylene glycol and polyethylene glycol?

The key difference between polyethylene glycol and propylene glycol is that polyethylene glycol is a polymer, whereas propylene glycol is a single molecular compound that can be named a diol. … Propylene glycol is a viscous, colorless liquid, having the chemical formula CH3CH(OH)CH2OH.

What exactly is polyethylene glycol?

Polyethylene glycol 3350 is used to treat occasional constipation. Polyethylene glycol 3350 is in a class of medications called osmotic laxatives. It works by causing water to be retained with the stool. This increases the number of bowel movements and softens the stool so it is easier to pass.

Is Ibuprofen a polyethylene glycol?

Each green, transparent, gelatin capsule contains 200 mg of ibuprofen. Nonmedicinal ingredients: FD&C Green No. 3, gelatin, polyethylene glycol, potassium hydroxide, purified water, sorbitan, sorbitol, and titanium dioxide. Each beige-brown, gelatin-coated gel caplet, contains 200 mg of ibuprofen.

How is ethylene glycol manufactured?

Ethylene glycol production and purification. Ethylene oxide is reacted with CO2, forming ethylene carbonate, which is then hydrolyzed to form MEG and CO2. Both reactions are carried out in the liquid phase using homogeneous catalysts. … The catalyst is separated and recycled to the ethylene carbonate reactors.